In pharmacology, tolerance refers to

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $9.99Unlock all

Explore the fundamental aspects of neuroscience with our engaging test on brain structure, neurons, and nervous system functions. Gain deeper insights through flashcards and multiple-choice questions. Hints and explanations provided for optimal learning. Prepare for your exam with confidence!

Multiple Choice

In pharmacology, tolerance refers to

Explanation:
Tolerance is a decreased responsiveness to a drug after repeated use, so more of the drug is needed to achieve the same effect. This can arise from changes in the body such as receptor desensitization or downregulation (pharmacodynamic tolerance) or from faster metabolism of the drug (pharmacokinetic tolerance). It’s distinct from withdrawal, which are symptoms that occur when stopping use, and from a predisposition to use. So the idea that the drug’s effect diminishes with continued use, requiring higher doses, best captures tolerance.

Tolerance is a decreased responsiveness to a drug after repeated use, so more of the drug is needed to achieve the same effect. This can arise from changes in the body such as receptor desensitization or downregulation (pharmacodynamic tolerance) or from faster metabolism of the drug (pharmacokinetic tolerance). It’s distinct from withdrawal, which are symptoms that occur when stopping use, and from a predisposition to use. So the idea that the drug’s effect diminishes with continued use, requiring higher doses, best captures tolerance.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy